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The SOX4/EZH2/SLC7A11 signaling axis mediates ferroptosis in calcium oxalate crystal deposition-induced kidney injury

Cell 53 , 10441052 (2014)

second, focusing on high-risk cohorts, such as patients with MASH-related compensated cirrhosis, using dynamic contrast-enhanced ultrasound (DCE-US) to monitor de novo nodule emergence and evolution (e.g., arterial phase hyperenhancement) as surrogate endpoints for preliminary chemopreventive assessment

That's also where diabetic peripheral neuropathy adds another layer of complexity impaired circulation and nerve signaling make the already-limited healing environment in foot tissue even harder to overcome without targeted support