Mutation HOXB13 c.853delT in Martinican prostate cancer patients
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Medications: antibiotics and certain inflammation reducers, like nonsteroidal anti-inflammatory drugs (NSAIDs) Medical treatments: radiation therapy or blood transfusions Physical stimuli: exercise, tight clothing, or exposure to heat, cold, or sunlight Viral infections: mononucleosis, COVID19, and hepatitis Bacterial infections: strep throat and urinary tract infections Allergic reactions to latex, nickel, insect bites or stings, and certain foods can also produce acute hives
The mechanism involves: Cholinergic antagonism -- cortistatin reduces cortical arousal by antagonizing acetylcholine-mediated excitation, effectively dampening the wake-promoting cholinergic system that maintains cortical desynchronization during wakefulness EEG synchronization -- the transition from wakefulness to SWS is characterized by increasingly synchronized, high-amplitude delta waves on EEG