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Nanocarriers attributed to the rapid development of nanotechnology, which exhibit distinct advantages in anti-tumor drug targeting delivery [30,31,32]

While DHODH inhibitors, including brequinar, were previously reported to sensitize to ferroptosis [50], our findings elucidate that their sensitizing effect on ferroptosis of these compounds is achieved not through DHODH inhibition but via off-target inhibition of FSP1

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It is made up of three amino acids: cysteine, glutamate, and glycine