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In addition, it is emerging as a promising adjuvant in the fight against COVID-19 due to its potential to activate NFE2-related factor-2 (Nrf2) and decrease inflammatory cytokines [25]

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161 Research into the role of small leucine-rich proteoglycans (SLRPs) in the ACL, such as decorin and biglycan, has shown that these molecules interact with collagen fibers to regulate fibrillogenesis and ECM organization