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Because drugs that increase dopamine have the potential for abuse, Volkows report concluded, these results suggest that risk for addiction in vulnerable persons merits heightened awareness. (Cephalon, in a response to the report, notes that Provigils label urges physicians to monitor patients closely, especially those with a history of drug abuse.) On the Web site Erowid, where people vividly, and anonymously, report their experiences with legal and illegal drugs, some modafinil users have described a dependency on the drug

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In a study on mice melanoma model, LCP NPs delivered the BRAFV600E peptide to mature DCs and presented antigens in C57BL6 mice