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A GSL Switch is Unlikely in the Current Climate Despite a recent drive by the Department of Health and Social Care (DHSC) to encourage the reclassification of certain medicines (like those for pain, sleep aids, and skin conditions) to P or GSL status, a switch for injectable B12 is not on the cards

& Forsdyke, D

B-100 complex can interfere with other medicines including but not limited to: levodopa, medicines containing oestrogen, hydrazine, certain anti epileptic drugs, phenobaritone, phenytoin, immunosuppressants and some drugs used to treat infections such as isoniazid, pyrazinamide, cycloserne and penicillamine

A codified approach is needed to determine the potential indications of a search for high serum cobalamin and the practical clinical strategy to adopt upon discovery of elevated cobalamin levels