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Continuous electrical current and zinc sulphate administered by transdermal iontophoresis improves skin healing in diabetic rats induced by alloxan: morphological and ultrastructural analysis. Accessed: Jan

Second, it argues against a pure placebo effect, because placebo responses tend to diminish more gradually

B12 injection shots can usually be felt within 24 hours (and a change should show in blood tests after a month or two) A high dose of B12 oral supplementation takes the same time as an injection: roughly 24 hours to feel an improvement and then up to 2 months to show in blood markers

But if you need replacement tablets of vitamin B12, these will usually be in the form of cyanocobalamin