BPC-157 heeft een korte plasmahalfwaardetijd (in de orde van minuten intraveneus ), maar het systemische effect overstijgt de farmacokinetiek
ESTS 2017, 2017
antioxidants including Glutathione ethyl ester (Cayman Chemical Company 14953), 2,2,6,6-Tetramethylpiperidine 1-oxyl (TEMPO, Sigma-Aldrich 214000-1 G), mitochondrial-targeted TEMPO (mitoTEMPO, Sigma-Aldrich SML0737-25MG), mitoCoQH2 (Mitoquinol, Cayman Chemical Company CAY89950), and CoQ10 (Coenzyme Q10, Sigma-Aldrich C9538)
Transcriptomic analyses of laser capture microdissected neurons from postmortem human AD revealed that NFT-containing neurons expressed signaling pathways consistent with cellular senescence, including SCAPs, upreguled pro-survival and inflammatory pathways and downregulated cell death pathways (35)