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These molecular alterations compromise sperm function, reducing their motility, fertilization capacity, and genetic integrity

Motor learning strongly stimulates the production of ITPR2 + OPCs, which then differentiate into OLGs, contributing to early learning by facilitating electrical transmission (Marques et al., These differences probably account for remyelination occurring later in the cortex than in the CC: after acute cuprizone-induced demyelination, OPC repopulation and differentiation is much faster in the CC than in the cortex, resulting in later, incomplete remyelination in the cortex (Gudi et al., Subventricular Zone-Derived Neural Progenitors Evidence for Subventricular Zone-Derived Oligodendrogenesis In the adult brain, the wall of the lateral ventricle is a stem cell niche with a unique cellular and extracellular organization (Mirzadeh et al., 2008

Mol Hum Reprod 25:433444 Oakberg EF (1979) Timing of oocyte maturation in the mouse and its relevance to radiation-induced cell killing and mutational sensitivity

alternative or additional contraception methods are recommended for 4 weeks after initiation and dose increases