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The result is a systems-level approach to digestive health, with butyrate at the center as the key metabolite.

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Given that both diet composition and adiposity can each substantially impact the gut microflora in obese mice 24 , we conducted a secondary endpoint study using animals given the same series of diets to test the hypothesis that NNMTi treatment combined with LD, but not LD alone, shifts the cecal microbiome profile of obese animals to be similar to age-matched LD controls that were never given a high-fat diet

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It's the kind of procedural discipline that separates good research from great research

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When in reality, MOTS-c and 5-Amino-1MQ address metabolic dysfunction through distinct, non-overlapping biological mechanisms

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