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In addition, it is thought that the mechanisms that ensure PQC in the nucleus are distinct from those of other organelles [108, 109], an example being the exclusive use of K48-linked ubiquitin chains required for proteasomal degradation of misfolded proteins, and thus independency of K11-specific ligases and chaperones [110]

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Molecular Formula : CHN Molecular Weight : 159.21 g/mol PubChem CID : 950107 CAS Number : 42464-96-0 Synonyms : 5-amino-1-methylquinolinium Source: PubChem In controlled laboratory settings, 5-Amino-1MQ may be used to investigate how NNMT modulation affects NAD+ availability, redox balance, and related metabolic pathways