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Elevated levels of serum antibodies against SYN have also been reported in a comparison of sera from PD patients with AD patients and controls (100)

Mitochondria as systemic supplements of the cardio-cerebral axis As the central organelles of energy metabolism, mitochondria play a key role as systemic regulatory factors in the highly metabolically active functional axis comprising the heart and brain

Foxp3 itself inhibits glycolysis and promotes oxidative phosphorylation (OXPHOS), while Foxp3 deficiency dysregulates mammalian target of rapamycin complex 2 (mTORC2) and promotes glycolysis (132, 142)

Each one does a specific job