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Both CDCA and deoxycholic acid (DCA) demonstrate positive inotropic effects (enhanced LVDP, dp/dt max, muscle strip tension) and negative chronotropic effects in isolated rat hearts via calcium-dependent mechanisms (Gao et al., 2021)

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[PubMed] Johansen PB, Nowak J, Skjaerbaek C, Flyvbjerg A, Andreassen TT, Wilken M, Orskov H

According to the review, nano-co-delivery of natural products with chemotherapeutic agents is expected to be the basis of new tumor therapeutic strategies that facilitate the development and translation of anticancer drugs (256)