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Open Access Maced J Med Sci 9:716726

In vivo studies Experimental work Animals were maintained under specific-pathogen-free conditions and in compliance with the Northern Ireland Department of Health (under PPL 2874 and 2960) regulations with approval from the QUB Animal Welfare and Ethical Review Body

How AOD-9604 Works at the Cellular Level AOD-9604 exerts its fat-reducing effects through activation of beta-3 adrenergic receptors located predominantly in adipose (fat) tissue

The stimulation of these transcription factors can lead to the expression of over 500 different genes, including those for growth factors, inflammatory cytokines, chemokines, cell cycle regulatory molecules, and anti-inflammatory molecules