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In the early stages of Alzheimers we see a reduction in the metabolic activity of neurons and glucose uptake, Muoz continues, and this fits perfectly with the fact that these oligomers do not kill neurons immediately, because neuronal death occurs when severe symptoms are observed (or vice versa), such as major memory losses and lack of spatial awareness

Rocamora N, Welker E, Pascual M, Soriano E (1996)

The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species

JAK inhibition using tofacitinib for inflammatory bowel disease treatment: a hub for multiple inflammatory cytokines