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Vitamin B12 also plays a key role in DNA synthesis, supports cell growth and repair, and contributes to energy metabolism

Manipulation of genes encoding enzymes for, e.g., folate biosynthetic and salvage pathway, polyglutamylation, and folate binding proteins, has been carried out with some achievements 2,10,25,34,303,310,560,752,754,776,791,792,793,794,795,796,797,798,799,800,801,802

Yeast has a high content of folate, but also the ability to synthesize the vitamin during fermentation, and this may compensate for folate losses during baking

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