Hepatic SOS results from occlusion of central and sublobular hepatic veins, typically related to therapy for bone marrow transplant SOS generally resembles Budd-Chiari syndrome, but venous obstruction in SOS occurs more distally, closer to the liver SOS prophylaxisheparin, prostaglandins, or ursodeoxycholic acid Established SOSmanagement is generally supportive
give the medication if the potential benefit outweighs the risk Positive evidence of fetal risk is available, but the benefits may outweigh the risk if the disease is life-threatening or serious Studies in animals or humans show fetal abnormalities
Los estudios (PMID 30333099, PMID 28234274) han explorado su influencia en modelos de reparacin de tendones, ligamentos y tejido conectivo, as como su interaccin con el eje intestino-cerebro, una va de comunicacin bidireccional entre el sistema digestivo y el sistema nervioso central
Not all patients benefit equally