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[DOI] [PubMed] [Google Scholar] Pasquini M, Biondi M
Initial assessment should include: Detailed medical and sexual history, including medication review Cardiovascular risk assessment (e.g., QRISK3 score) Examination of external genitalia and secondary sexual characteristics Blood pressure measurement Blood tests: fasting glucose or HbA1c, lipid profile, early morning (before 11am) total testosterone (repeat if low), consider prolactin and thyroid function if clinically indicated First-line pharmacological treatment: Phosphodiesterase type 5 (PDE5) inhibitors are the mainstay of ED treatment and include sildenafil, tadalafil, vardenafil, and avanafil
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