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All subjects (patients and healthy volunteers) gave their written informed consent before participation

This review consolidates the current understanding of these individual interventions and highlights the promising, yet under-explored, potential of their combined application in CRC management

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When assayed with ultrafiltered flavan-3,3,4-triol ( 4 ), oxidation of C13 in the wild-type enzyme resulted in a drastically lower formation of cyanidin ( 8 ), while we observed no effect for the C13S variant (Fig