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Through its modulation of the NNMT-SAM-NAD+ axis, it enhances energy expenditure and supports more efficient utilization of fat stores for energy, making it a strong candidate in studies exploring metabolic optimization and obesity control

Al, obese Zucker rats were received a dose of 500 micrograms/kg of body weight over the course of 19 days

Published AOD-9604 trials did not report patterns of fluid retention or edema, suggesting this side effect is not a concern with the peptide fragment

Identifies 5-Amino-1MQ as a potent, cell-permeable NNMT inhibitor and evaluates its effects on adipocyte differentiation and metabolic markers in vitro and in vivo