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Most people in the general population can get enough vitamin B12 from a balanced diet

Absorption problems Even with adequate intake, absorption can be reduced by: Certain gastrointestinal conditions affecting the stomach or small intestine Some medications Age-related reduction in stomach acid (which can affect absorption) Autoimmune gastritis (often historically referred to as pernicious anaemia) This is a well-recognised cause of B12 deficiency and may require ongoing management

in fact, levels of DHA were decreased in rats fed 10:1 and 25:1 ratios of n-3:n-6FA

Its use typically requires careful monitoring and individualized planning