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For the proper delivery of the drug encapsulated in the liposome, it is imperative to take into consideration the properties of both the stratum corneum and the drug, while considering the site of application, body temperature, and the blood flow of the skin

Measurements using body composition methods (DEXA, bioimpedance, caliper) are more informative than scale weight alone, as AOD-9604 may preserve lean tissue while selectively reducing fat mass