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AOD9604 and Energy Balance Research In obese ob/ob and lean C57BL/6J mice treated for 14 days via mini-osmotic pumps, AOD9604 significantly reduced body weight gain in obese mice, associated with increased in vivo fat oxidation and increased plasma glycerol levels as an index of enhanced lipolysis without the hyperglycaemia or reduced insulin secretion associated with intact hGH treatment

Typically, 1 ampoule 2-3 times weekly for therapeutic use, or once weekly/monthly for maintenance, administered intramuscularly or intravenously

The intramolecular disulfide bond between its two cysteine residues is believed to be important for maintaining its active conformation

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