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blood Cu, SOD1, glutathione peroxidase, ceruloplasmin, triglycerides, total cholesterol, low-density lipoprotein, high-density lipoprotein, coenzyme-Q10, and transferrin l

While current research on combination therapies predominantly focuses on downstream therapeutic biomarkerssuch as pro-inflammatory cytokines (e.g., TNF-, IL-1, IL-6), oxidative stress markers (e.g., MDA, SOD), and mucosal healing indicators (e.g., MUC-2, tight junction proteins)investigations into upstream signaling pathways (e.g., Notch, MAPK/ERK) remain preliminary

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Thus, DNTB method grants measurement of free GSH, oxidized GSH (GSSG) and total content of GSH (free GSH + GSSG) in a multi-step approach in biological samples