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Age-related considerations Clinical trials included adults across a range of ages, but specific data on elderly populations is limited

For this first analysis, other treatments (e.g., hydroxyurea - see below) were excluded

Assessment of schistosomula viability after treatment by NO/ONOO donors Two approaches, methylene blue staining [52] and quantification of lactate production [53], were employed to concurrently evaluate the viability of schistosomula after NOR-5 or SIN-1 treatment

Front Immunol 9:1363 Jaeger C, Tischkau SA (2016) Role of aryl hydrocarbon receptor in circadian clock disruption and metabolic dysfunction