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Joo H, Maskery BA, Alpern JD, Chancey RJ, Weinberg M, Stauffer WM

Liu X et al 2010)

In Phase 2 trials involving participants with type 2 diabetes, HbA1c improved by up to 2.2%, with 82% of participants reaching HbA1c levels at or below 6.5%

Indications: Treatment of orthostatic hypotension in adult patients with symptomatic neurogenic orthostatic hypotension (nOH) caused by: Parkinson's disease multiple system atrophy pure autonomic failure) dopamine beta-hydroxylase deficiency non-diabetic autonomic neuropathy Pharmacokinetics: administered orally converted by DOPA decarboxylase into norepinephrine Side Effects: A new drug