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AOD-9604 works through fat metabolism, not appetite suppression like GLP-1 medications

Cortisol is a secondary responder whereas norepinephrine and epinephrine are the primary responders that initiate the physiological changes, which kick the body into action when under stress

The subsequent increase in metabolic rate leads to a reduction in white adipose tissue and has been shown to produce significant weight loss in preclinical studies without affecting appetite

Children on sermorelin will have their growth (height and weight) tracked carefully over time, and bone age X-rays periodically, to see if they are responding in terms of growth velocity