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(2011PLoS ONE, 6 (3) DOI: 10.1371/journal.pone.0018046 40 Smith, Phase II Metabolism, UNC Chapel Hill, 8/2012 Inducers of GlucuronidationInduction of UGTs, and other Phase II enzymes is usually modest, several fold, in contrast to possible induction noted for P450s.General inducers: PAH analogs, such as 3methylcholanthrene and naphthoflavone, are not very specific for UGT isozymes and also induce P450s.Phase II selective inducers are reported to activate the Antioxidant Response Element (ARE), e.g

It helps protect cells against oxidative stress caused by free radicals and plays an important role in maintaining overall cellular health

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