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Calculations of pKa for individual Cys residues were performed with Propka 3 which gives an approximation of the pKa based on a solution of the Boltzmann equation (Rostkowski et al., 2011)

87 The lack of robust human data is the elephant in the room: we simply dont have the clinical trials to know if the amazing results in rats will translate to people, or if long-term use might introduce serious side effects

Abstract Depressive disorders are among the most common psychiatric conditions and contribute to significant morbidity

The method involves removing an individual component from a known mixture of aroma chemicals and see how it contributes to the mix, explains Waterhouse