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Keywords: high-fat diet, marmelosin, streptozocin, type II diabetes Introduction Type 2 Diabetes Mellitus (T2DM) belongs to a chronic metabolic disorder with a rapidly escalating global incidence, primarily attributed to contemporary lifestyle factors such as excessive consumption of energy-rich diets and diminished physical activity

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Targeting NCOA4 may be an important protocol for regulating unstable iron pools and controlling susceptibility to ferroptosis