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This approach follows general peptide cycling logic and is a reasonable precaution given limited long-term human data

Cagrilintide has a lower treatment discontinuation rate and causes less vomiting

Phylum-level analysis (Figure S1D) revealed that the VPA-ASD group was dominated by Pseudomonadota (Proteobacteria), with elevated Deferribacterota and Campylobacterota, and severe depletion of Bacteroidota and Verrucomicrobiota