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Increased glutathione (the bodys master antioxidant) in the plasma and brain (proven at a dose of 18 mg of sulforaphane/day) Increased brain glutathione levels have been shown to be beneficial for treating neurological disorders and reducing symptoms of autism through the reduction of oxidative stress Other studies in which participants were dosed with 10 grams of broccoli sprout extract per day found that: Oxidized LDL, thought to play a causal role in cardiovascular disease, was reduced Serum triglycerides were reduced by 18-19% Atherogenic index was decreased by 50% Sulforaphane increases the excretion of harmful carcinogens like benzyne and acrolein, both of which are found in cigarette smoke and air pollution, by up to 60% How so

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All the members form heterodimers with small Maf proteins through leucine zipper motifs and bind to the ARE consensus sequence through basic regions, suggesting that the bZip structure of Nrf2 shares many common properties with that of other CNC members