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87 A trial in patients with trichotillomania (hair pulling, see also below under obsessive compulsive disorders) found a clinically significant improvement in depressive symptoms in 44% of patients, compared with 4% in the placebo group, a statistically significant difference

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In Ldlr / Leiden mice, only the combined intervention with nicotinamide riboside, rather than either monotherapy, significantly attenuated obesity and hepatic steatosis, accompanied by coordinated upregulation of genes involved in fatty acid oxidation and insulin signaling (61)