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GH response amplitude is similar between the two peptides

ROLE OF IGF-1 SIGNALING IN MODULATING PTH ACTION IN BONE Circulating PTH in its various molecular forms is secreted from the parathyroid glands ( In vivo , intermittent administration of PTH leads to a rapid increase in osteocalcin, alkaline phosphatase, and collagen mRNA levels, suggesting its direct effect on osteoblast activity (Nishida et al., 1994

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