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8-OHdg (8-hydroxy-2-deoxyguanosine) is an oxidized base that has been identified and removed from the DNA, excreted in the urine

Collectively, these data support the conclusion that increased cellular GSSG accumulation in hepatocytes plays a critical role in the pathogenesis of NAFLD and may represent a potential therapeutic target for the treatment of NAFLD

doi: 10.1038/s41586-019-1170-y 83 LangXGreenMDWangWYuJChoiJEJiangLet al