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Potential cost By Hugh Pym, BBC health editor From nowhere to more than 2.5 million British users in under a decade - the e-cigarette story has moved at a dramatic pace But what about the cost of prescribing

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In human respiratory epithelial cells, in vitro exposure to third-hand smoke for 3 h resulted in changes in mitochondrial activity, which led to an adaptive activation of survival mechanisms, such as ATP synthesis and increased oxidative phosphorylation (Pozuelos et al., 2019)