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TB-500 retains sequence motifs associated with actin cytoskeleton modulation and cellular migration pathways

Site-directed mutagenesis and inhibition assays revealed that Phe-9 is potentially an important residue for the binding of the inhibitor S-hexyl glutathione (GTX) [77]

However, total glutathione showed that the use of this peptide was different since in CO23 strain treated with FLC this value was halved with respect to the MFCG treated indicating a depletion of the glutathione pool

Phase III - further modification and excretion [edit] After phase II reactions, the xenobiotic conjugates may be further metabolised