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These may include alterations in learning mechanisms, in mice indicated by lack of pairing of odor learning with aversive stimuli in newborn animals but the development of such an association 1012 days later

Not surprisingly, these last genera have been associated with the ability of reducing intestinal permeability, with consequent decrease of endotoxin levels and improvement of glucose tolerance and systemic inflammation [55]

[1] Spike-timing-dependent plasticity (STDP), where a presynaptic neuron firing just milliseconds before a postsynaptic neuron leads to synaptic strengthening (timing-based long-term potentiation LTP), while firing after the postsynaptic neuron causes weakening (timing-based long-term depression LTD)