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It has been extensively studied for its effects on telomerase activation an enzyme that helps lengthen telomeres, the DNA sequences that protect chromosomes from damage during replication

Importantly, the pathophysiological consequences of elevated NET components in the follicular microenvironment are supported by parallel evidence: multiple studies link increased oxidative stress and inflammatory mediators in follicular fluid to reduced oocyte competence, lower fertilization rates, and poorer embryo quality in women with PCOS, providing a biologically plausible pathway by which NET-derived DNA, histones, and proteases could impair gamete quality and fertilization success [55]

Sub-clinical mineral deficiencies can occur during periods of high energy demand, such as in young, growing cattle or during mating, calving and lactation, she said