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Patients who are most at risk of renal failure from DRESS are elderly individuals, those with pre-existing renal disease and DRESS caused by allopurinol.15,30,39 The lung is the third most frequently affected organ, with interstitial pneumonitis as the most common manifestation.39 The association with minocycline may lead to a higher incidence of pneumonitis.40 Cardiac involvement typically manifests as myocarditis or pericarditis and, on average, 70 days after the initial symptoms