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Excessive intake or long-term and frequent use of a large amount of Caffeine will lead to some negative side effects, such as anxiety, depression, chronic insomnia, and stomach problems

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Ladd's other notable film roles from this period included "The Reivers," "The Rebel Rousers" and "White Lightning." Meanwhile, Ladd acted steadily on television, picking up parts on "The Walter Winchell File," "Naked City," "Deadline," "The Detectives," "Perry Mason," "The Fugitive," "Gunsmoke" and other midcentury classics

Similar toxicity can occur when plants or seeds with similar nicotine-like substances in them are ingested (e.g