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Evidence Against the Gateway Hypothesis The strongest evidence challenging gateway drug theory as a universal mechanism includes: The National Institute of Justice (2018), after reviewing 23 peer-reviewed studies, concluded no causal link between cannabis use and other illicit drug use can be established, noting that statistical correlation persists across populations but direct pharmacological causation cannot be claimed from observational data alone

Many of the above chemical compounds are known to have severe negative health effects, e.g

Whether you live in close proximity to someone who routinely smokes, or you live in an area affected by wildfires, regular exposure to the microscopic particles found in smoke can have a devastating effect on your lungs and overall health

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