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4 All aged 4854 years with at least 20 years of experiences in teaching or leading activities at preparatory schools and never smoked, except one smokes heavily

The tabaqueros description of etiology of diseases, which first arise in the spirit-body, then in the energy-body, and only then manifest in the physical body, is interesting in conjunction with his stated mode of action of tobacco in terms of its effectiveness in the spiritual/energetic domain: It implies that from the Amazonian epistemic perspective, tobacco has the capacity to intervene in the process of pathogenesis at a level more fundamental than the physical

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In fact, a study found that moderate and low doses of nicotine can increase the resting metabolic rate by 6%