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Given the above considerations, we conducted a randomized controlled trial (RCT) to examine, in COPD patients receiving regular 12-week varenicline therapy, whether using varenicline for a 6-week gradual cessation before the target quit day (TQD), rather than starting 1 week before the TQD as currently labeled, would improve quit outcomes 30 weeks after randomization

Too much weight should not be put on such statistics, in part due to the small numbers involved, but smoking rates amongst children did not change much over the course of the next 30 years, suggesting that some groups of children were largely impervious to anti-smoking messages

Prevalence and clustering of preventable health risk factors Of all participants, 8.8% (45/514) reported smoking at any time during pregnancy, 16.1% (83/514) reported consuming alcohol during pregnancy and 57.1% (267/469) reported gestational weight gain that was above or below recommended levels