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Leading countries in Europe include Germany, the UK, and France, where key players like British American Tobacco and Imperial Brands are actively expanding their product lines

In recent years, electronic nicotine delivery systems (ENDS) have become increasingly popular

In a clinical study, it was demonstrated that cigarette smoking induces pyloric incompetence and increases the duodenogastric reflux (39), which may be due to the reduction in basal pyloric pressure induced by smoking (40), leading to mucosal injury in the stomach

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