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It has been reported that mutant p53 protein can negatively impact the cytotoxic effects of cisplatin treatment for NSCLC via the upregulation of NRF2, a transcription factor that was reported to contribute to the resistance of malignant cells to several anti-cancer drugs [205]

CategoryHealth Last Updated24/08/2022 How smoking harms the heart, clots blood and causes brain strokes A recent publication reported that 44.4% of global cancer deaths are attributable to three risk factors smoking, excessive alcohol consumption and a high BMI (overweight or obesity)

The film is one part psychological drama, neo-noir, police procedural, and a thrilling mystery