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Control arm The participants in the control arm (usual care) did not receive any intervention apart from the leaflet outlining the benefits of and advice on tobacco abstinence that every participant in the RCT received at recruitment

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An independent study found higher expressions of metallothionein (scavengers of ROS and metals and associated with immune diseases and cancers) in the cells of the lungs and liver from mice exposed to CS but not to IQOS smoke 33