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In previous work, our group combined Latent Transition Analysis (LTA) with Separable Temporal Random Graph Models (STERGMs) to examine selection homophily and peer influence processes in terms of the MECHANISMS study experimental measures of smoking and vaping norms (Montes et al., 2023)

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According to the protein misfolding avoidance hypothesis, natural selection disfavors the misfolding of highly expressed proteins, thereby constraining their evolution to minimize cytotoxicity 38