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1 Just as you wouldnt wind down with an espresso before bed, a cigarette prior to going to sleep actually introduces a powerful stimulus into the bloodstream which can cause insomnia and/or sleep-disordered breathing, rather than relaxing your body

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The concern is that users may assume that the permitted reduced exposure claim may translate to reduced risk and encourage IQOS use, especially among those who have not used nicotine products before

Using the Wald test criteria, we removed non-significant paths ( p -value greater than 0.05) that did not increase the model chi-square