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(mayoclinic.org) Why does cigarette smoke smell stay for so long

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They produce a mild toxin which, in large quantities could cause illness Research microbiologist Dr Steven Foley at the FDA's National Centre for Toxicological Research added other Bacillus species also present health concerns

it was John Rolfe who in 1612 obtained Spanish seeds, or Nicotiana tabacum , from the Orinoco River valleyseeds that, when planted in the relatively rich bottomland of the James River, produced a milder, yet still dark leaf that soon became the European standard